Led by sixth-year head coach Dale Lindsey, the Toreros compiled an overall record of 9–3 with a mark of 8–0 in conference play, winning the PFL title.

San Diego earned the conference's automatic bid to the NCAA Division I Football Championship playoffs, where the Toreros lost in the first round to Nicholls.

The team played home games at Torero Stadium in San Diego.

The PFL released their preseason all-PFL team on July 30, 2018, with the Toreros having four players selected.

[2] Offense Anthony Lawrence – QB Zack Nelson – FB Daniel Cooney – OL Defense Connor Spencer – DL