[2] The draw for the qualifying stages was held on 17 December 2018, 20:30 PYST (UTC−3), at the CONMEBOL Convention Centre in Luque, Paraguay.
Teams from the same association could not be drawn into the same tie, excluding the three winners of the first stage, which were allocated to Pot 2 and whose identity was not known at the time of the draw, and could be drawn into the same tie with another team from the same association.
If still tied, extra time was not played, and a penalty shoot-out was used to determine the winner (Regulations Article 29).
Tied 2–2 on aggregate, Deportivo La Guaira won on away goals and advanced to the second stage (Match C6).
Tied 2–2 on aggregate, Palestino won on penalties and advanced to the third stage (Match G4).
Tied 1–1 on aggregate, Caracas won on away goals and advanced to the third stage (Match G2).