[2][3] Tigre were the champions, beating Boca Juniors by a 2–0 score in the final match played at Estadio Mario Alberto Kempes in Córdoba.
Matchups in all rounds prior to the final were played as two-legged ties, with the team with the best placement in the league season hosting the second leg, whilst the final was played as a single match at a neutral ground.
If teams were tied on aggregate in all rounds prior to the final, the away goals rule was used.
In the final, 30 minutes of extra time would be played if both teams were tied, and if still tied at the end of extra time, the champions would be determined in a penalty shoot-out.
The 20 teams placed from seventh to twenty-sixth in the 2018–19 Superliga Argentina played in the first round of the competition.