In addition to the domestic league, Atlético Madrid participated in this season's editions of the UEFA Champions League and also participated in the Copa del Rey.

The season covered the period from 14 August 2020 to 30 June 2021, with the late start to the season due to the COVID-19 pandemic in Spain.

Total Income: €80M Net Income: €8M Win Draw Loss Source: Soccerway Source: La Liga The league fixtures were announced on 31 August 2020.

[3][4] The group stage draw was held on 1 October 2020.

[12] 1Player from reserve team (Atlético Madrid B).2Player left the club during the season.