2020–21 Louisville Cardinals men's basketball team

The team played its home games on Denny Crum Court at the KFC Yum!

Center in downtown Louisville, Kentucky as members of the Atlantic Coast Conference.

They were led by third-year head coach Chris Mack.

[1] The team declined an invitation to the NIT prior to the NCAA Tournament field being announced.

[2][3] When all teams were able to participate in the opening rounds of the NCAA tournament, the Cardinals season ended.