The 2021–22 season is Brescia Leonessa's 13th in existence and the club's 7th consecutive season in the top tier Italian basketball.
Supplier: Errea / Sponsor: Germani Note: Flags indicate national team eligibility at FIBA-sanctioned events.
Players may hold other non-FIBA nationalities not displayed.
(colours: Italian or homegrown players; foreign players; young players)