2021–22 Chamois Niortais F.C. season

and the club's eighth consecutive season in the second division of French football.

The team was excluded from Coupe de France this season.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss Source: Soccerway Source: Ligue 2 The league fixtures were announced on 25 June 2021.