In addition to the domestic league, Nice participated in this season's edition of the Coupe de France.

On 28 June 2021, reigning Ligue 1 manager of the year Christophe Galtier was appointed as the new head coach of Nice.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.