The 2021 Henry Ford Health System 200 was the 14th stock car race of the 2021 ARCA Menards Series season and 33rd iteration of the event.

[1] To fill out the podium, Corey Heim of Venturini Motorsports and Nick Sanchez of Rev Racing would finish second and third, respectively.

It is known as a "sister track" to Texas World Speedway as MIS's oval design was a direct basis of TWS, with moderate modifications to the banking in the corners, and was used as the basis of Auto Club Speedway.

Michigan International Speedway is recognized as one of motorsports' premier facilities because of its wide racing surface and high banking (by open-wheel standards; the 18-degree banking is modest by stock car standards).

The starting lineup was instead determined by car owner points for the 2021 season and provisionals.