The 2021 Tennessee Tech Golden Eagles football team represented Tennessee Technological University as a member of the Ohio Valley Conference (OVC) during the 2021 NCAA Division I FCS football season.

Led by fourth-year head coach Dewayne Alexander, the Golden Eagles compiled an overall record of 3–8 with a mark of 1–5 in conference play, tying for sixth place in the OVC.

Tech Golden played home games at Tucker Stadium in Cookeville, Tennessee.

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