SønderjyskE and Vejle BK finished the 2021–22 season of the Superliga in 11th and 12th place, respectively, and were relegated to the 1st Division.
They replaced AC Horsens and Lyngby Boldklub, who were promoted to the 2022–23 Danish Superliga.
Næstved BK and Hillerød won promotion from the 2021–22 Danish 2nd Division.
Note: Flags indicate national team as has been defined under FIFA eligibility rules.
Positions by round The bottom 6 teams will compete to avoid the 2 relegations to the 2023–24 Danish 2nd Division.