The 2022–23 Michigan State Spartans women's basketball team represented Michigan State University as a member of the Big Ten Conference during the 2022–23 NCAA Division I women's basketball season.

The Spartans, led by 16th-year head coach Suzy Merchant played their home games at Breslin Center in East Lansing, Michigan.

[2] On January 28, 2023, head coach Suzy Merchant was involved in an automobile crash which led to her being hospitalized.

[6] The team's statistical leaders included Kamaria McDaniel with 427 points scored, DeeDee Hagemann with 146 assists, and Taiyier Parks with 152 rebounds.

In the Big Ten tournament they defeated Purdue in the before losing to Ohio State in the quarterfinals.