The 2024–25 Michigan State Spartans women's basketball team represents Michigan State University during the 2024–25 NCAA Division I women's basketball season.

The Spartans are led by second-year head coach Robyn Fralick and play their home games at the Breslin Center in East Lansing, Michigan as members of the Big Ten Conference.

They lost in the quarterfinals of the Big Ten tournament to Nebraska.

They received an at-large bid to the NCAA tournament as the No.

8 seed in the Albany Regional 1 where they lost in the first round to North Carolina.