The 2015–16 Michigan State Spartans women's basketball team represented Michigan State University during the 2015–16 NCAA Division I women's basketball season.

The Spartans, led by ninth year head coach Suzy Merchant, played their home games at the Breslin Center and were members of the Big Ten Conference.

They advanced to the championship game of the Big Ten women's tournament, where they lost to Maryland.

They received an at-large bid to the NCAA women's tournament, where they defeated Belmont in the first round before losing to Mississippi State in the second round.

Suzy Merchant (Central Michigan) Amaka Agugua (Hofstra) NcKell Copeland (Jacksonville State) Mark Simons (Michigan State) Roster [1]