The regular season began on June 9 and ended on October 29, with 18 games played per team over 21 weeks.
The league released the season's full schedule on December 16, 2021, just four days after the 108th Grey Cup.
[1] The Toronto Argonauts played a neutral site game on July 16 against the Saskatchewan Roughriders at Raymond Field, in Wolfville, Nova Scotia; with the stadium capacity increased from 3,000 to 10,000.
All previous regular season games of the Touchdown Atlantic series were held in Moncton, New Brunswick.
[22] On April 27, the league announced a series of rule changes with the intention of improving game flow, and increasing offensive production.
[24] Pending free agents and teams were able to negotiate offers for one week starting January 30 and ending February 6.
The CFL continued to be broadcast on TSN and RDS across all platforms in Canada as part of their current contract.
[28] The CFL entered a new partnership with Visaic providing streaming options for 130 countries and territories around the world.