In addition to the national league, Atlético Mineiro participated in this season's editions of the Campeonato Mineiro, the Copa do Brasil, Copa Libertadores and the Supercopa do Brasil.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Undisclosed fees are not included in the transfer totals.

Source: Soccerway The draw for the round of 16 was held on 27 May 2022.