The 2022 Engie Open Nantes Atlantique is a professional tennis tournament played on indoor hard courts.

It is the eighteenth edition of the tournament which is part of the 2022 ITF Women's World Tennis Tour.

It takes place in Nantes, France between 31 October and 6 November 2022.

[1] The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received entry as a lucky loser: