The 2022 Slovak Open was a professional tennis tournament played on hard courts.

It was the 24th edition of the tournament which was part of the 2022 ATP Challenger Tour and the ninth edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour.

It took place in Bratislava, Slovakia between 7 and 20 November 2022.

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following players received wildcards into the singles main draw: The following player received entry into the singles main draw using a protected ranking: The following players received entry from the qualifying draw: The following player received entry as a lucky loser: