In the MotoGP class, Marc Márquez returned to the track after missing the Argentine GP due to a case of diplopia.

[1] In the Moto2 class, Keminth Kubo missed the Grand Prix, as he was denied a visa for this event in the United States.

[3] In the Moto3 class, Gerard Riu replaced David Muñoz on the KTM of the Boé SKX team.

The two drivers hold a significant advantage over their closest competitors, Izan Guevara, Kaito Toba, and Deniz Öncü, who follow with 28, 27, and 26 points, respectively.

In the constructors' championship standings, Honda leads with 70 points, holding a five-point advantage over GasGas.