The 2025 Charleston Southern Buccaneers football team will represent Charleston Southern University as a member of the OVC–Big South Football Association during the 2025 NCAA Division I FCS football season.

They are expected to be led by Gabe Giardina in his third season as head coach.

The Buccaneers play their home games at Buccaneer Field in Charleston, South Carolina.

[1][2][3][4] [5][4] [6] at FirstBank Stadium • Nashville, TN at Brooks Stadium • Conway, SC at Buccaneer Field • North Charleston, SC at Zable Stadium • Williamsburg, VA at Buccaneer Field • North Charleston, SC at Ernest W. Spangler Stadium • Boiling Springs, NC at Buccaneer Field • North Charleston, SC at Hanson Field • Macomb, IL at Buccaneer Field • North Charleston, SC at Houck Stadium • Cape Girardeau, MO at Graham Stadium • Martin, TN at Buccaneer Field • North Charleston, SC