The 2025 Western Illinois Leathernecks football team will represent Western Illinois University as a member of the OVC–Big South Football Association during the 2025 NCAA Division I FCS football season.

They are expected to be led by second-year head coach Joe Davis.

The Leathernecks play their home games at Hanson Field in Macomb, Illinois.

[1][2][3][4] [5] [6] at Memorial Stadium • Champaign, IL at Martin Stadium • Evanston, IL at Hanson Field • Macomb, IL at Roos Field • Cheney, WA at Hanson Field • Macomb, IL at Tucker Stadium • Cookeville, TN at Graham Stadium • Martin, TN at Hanson Field • Macomb, IL at Nissan Stadium • Nashville, TN at Hanson Field • Macomb, IL at Hanson Field • Macomb, IL at Ernest W. Spangler Stadium • Boiling Springs, NC