2GO Masagana is a passenger ferry and flagship of the Philippine shipping company 2GO Travel that went into service in 2003.

She is the sister ship of MV 2GO Maligaya, formerly Yamato, also from Hankyu Ferry.

She and her sister ship are the largest passenger vesels ever to sail in the Philippines, surpassing MV Princess of the Stars of Sulpicio Lines.

She succeeded the outgoing New Seto which was sold to Aboitiz Transport System in the Philippines as MV Superferry 18.

In 2020, after the new generation "Yamato" was launched, it was planned to be fitted with desulfurization equipment and transferred to the Izumi - Ōtsu - Shinojima (Shin-moji) route in the fall of the same year, where cargo demand was high, to handle two additional round trips per week.