3',5'-cyclic-AMP phosphodiesterase

3′,5′-cyclic-AMP phosphodiesterase (EC 3.1.4.53, cAMP-specific phosphodiesterase, cAMP-specific PDE, PDE1, PDE2A, PDE2B, PDE4, PDE7, PDE8, PDEB1, PDEB2) is an enzyme with systematic name 3′,5′-cyclic-AMP 5′-nucleotidohydrolase.

[1][2][3][4][5][6] It catalyses the following reaction This enzyme requires Mg2+ or Mn2+ for activity.