3,8-Dihydrodiligustilide is a nonsteroidal phytoprogestogen that is found in Ligusticum chuanxiong.

[1][2] It is a potent agonist of the progesterone receptor (EC50 = 90 nM).

[1] Another compound in the plant, riligustilide, is also a phytoprogestogen, but is almost 1,000-fold less potent and is very weak in comparison (EC50 ≈ 81 μM).

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