In enzymology, a 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME), whereas its two products are ADP and 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-MEP).
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor.
This enzyme is also called CDP-ME kinase, and IspE.
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1OJ4, 1UEK, 2V2Q, 2V2V, 2V2Z, 2V34, and 2V8P.
This EC 2.7 enzyme-related article is a stub.