In enzymology, a 4-chlorobenzoate dehalogenase (EC 3.8.1.6) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 4-chlorobenzoate and H2O, whereas its two products are 4-hydroxybenzoate and chloride.
This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds.
The systematic name of this enzyme class is 4-chlorobenzoate chlorohydrolase.
This enzyme is also called halobenzoate dehalogenase.
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1BVQ, 1JXZ, and 1NZY.