The 58th Regiment Illinois Volunteer Infantry was an infantry regiment that served in the Union Army during the American Civil War.

The 58th Illinois Infantry was organized at Chicago, Illinois and mustered into Federal service on December 26, 1861.

The regiment was mustered out on April 15, 1866.

The regiment suffered 8 officers and 75 enlisted men who were killed in action or mortally wounded and 4 officers and 211 enlisted men who died of disease, for a total of 298 fatalities.

This article about a specific military unit of the American Civil War is a stub.