It is located at and over both 75th Street and South Chicago Avenue, and is 9.3 miles (15.0 km) away from the northern terminus at Millennium Station.

No parking is available for this station, however the Chicago Transit Authority does provide bus service here.

The station and the neighborhood that surrounds it were named for the Grand Crossing, an on-grade railway junction constructed in 1853 by mutual agreement between the Lake Shore and Michigan Southern Railway (New York Central) and the Illinois Central Railroad in settlement of a right-of-way feud.

By 1912, this on-grade crossing was eliminated when the successor line to the LS & MS was elevated.

Media related to 75th Street (Grand Crossing) (Metra) at Wikimedia Commons