3Q4T, 3SOC, 4ASX9211480ENSG00000121989ENSMUSG00000052155P27037P27038NM_001278579NM_001278580NM_001616NM_007396NP_001265508NP_001265509NP_001607NP_031422Activin receptor type-2A is a protein that in humans is encoded by the ACVR2A gene.

This gene encodes activin A type II receptor.

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.

Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.

Type II receptors are considered to be constitutively active kinases.