392255242316ENSG00000156466ENSMUSG00000051279Q6KF10P43028NM_001001557NM_013526NP_001001557NP_038554Growth differentiation factor 6 (GDF6) is a protein that in humans is encoded by the GDF6 gene.

[5] GDF6 belongs to the transforming growth factor beta superfamily and may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins,[6] and control eye development.

GDF6 has been shown to play an important role in the patterning of the epidermis[9] and bone and joint formation.

[9] GDF6 interacts with bone morphogenetic proteins (BMPs) to form heterodimers that may work to regulate neural induction and patterning in developing embryos.

Through this experiment, the scientists were able to directly link GDF6 with several skull and vertebral joint disorders, such as scoliosis and chondrodysplasia, Grebe type.