[5][6] It is a member of the ADAM family of extracellular matrix metalloproteinases.

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family.

Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.

This gene is highly expressed in the brain and may function as an integrin ligand in the brain.

This article on a gene on human chromosome 2 is a stub.