4NRE24711688ENSG00000179593ENSMUSG00000020891O15296O35936NM_001141NM_001039130NM_001039131NM_009661NP_001034219NP_001034220NP_001132NP_033791Arachidonate 15-lipoxygenase type II is an enzyme that in humans is encoded by the ALOX15B gene.
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides.
15-LOX-2 has 38-39% amino acid sequence identity to human 15-LOX-1 and 12-lipoxygenase and 44% amino acid sequence identity to human 5-lipoxygenase.
Alternatively spliced transcript variants encoding different isoforms have been described.
This article on a gene on human chromosome 17 is a stub.