All of the GPUs of the series are produced in 28 nm format and use the Graphics Core Next (GCN) micro-architecture.

[11] The R9 380/X along with the R9 Fury & Nano series were AMD's first cards (after the earlier R9 285) to use the third iteration of their GCN instruction set and micro-architecture.

Any ancillary ASICs present on the chips are being developed independently of the core architecture and have their own version name schemes.

The AMD Eyefinity branded on-die display controllers were introduced in September 2009 in the Radeon HD 5000 series and have been present in all products since.

Originally introduced with the previous generation R9 285 and R9 290 series graphics cards, this feature allows users to run games with higher image quality by rendering frames at above native resolution.

Vulkan 1.2 requires GCN 2nd gen or higher with the Adrenalin 20.1 and Linux Mesa 20.0 drivers and newer.

The following table shows features of AMD/ATI's GPUs (see also: List of AMD graphics processing units).

This may be different for the AMD FirePro brand, which is based on identical hardware but features OpenGL-certified graphics device drivers.

[47] This driver still requires proprietary microcode to operate DRM functions and some GPUs may fail to launch the X server if not available.