ANAPC7

3FFL, 4UI9, 5A31, 5G04, 5G055143456317ENSG00000196510ENSMUSG00000029466Q9UJX3Q9WVM3NM_001385211NM_001385212NM_019805NP_001131136NP_057322NP_057322.2NP_062779Anaphase-promoting complex subunit 7 is an enzyme that in humans is encoded by the ANAPC7 gene.

[5] Multiple transcript variants encoding different isoforms have been found for this gene.

This gene encodes a tetratricopeptide repeat containing component of the anaphase-promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination.

The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators.

This article on a gene on human chromosome 12 is a stub.