APOBEC

APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide") is a family of evolutionarily conserved cytidine deaminases.

The APOBEC family of proteins perform mRNA modifications by deaminating cytidine bases to uracil.

RNA editing by APOBEC-1 requires homodimerization and this complex interacts with RNA-binding proteins to form the editosome.

[5][6] APOBEC family proteins are widely expressed in cells of the human innate immune system.

[tone] Human genes encoding members of the APOBEC protein family include: This protein-related article is a stub.

Example of a member of the APOBEC family, APOBEC-2 . A cytidine deaminase from Homo sapiens . [ 1 ]