2CXY, 2EH957492239985ENSG00000049618ENSMUSG00000069729Q8NFD5E9Q4N7NM_017519NM_001363725NM_001371656NM_001374820NM_001374828NM_001085355NP_059989NP_001350654NP_001358585NP_001361749NP_001361757NP_001078824AT-rich interactive domain-containing protein 1B is a protein that in humans is encoded by the ARID1B gene.

[5] ARID1B is a component of the human SWI/SNF chromatin remodeling complex.

Germline mutations in ARID1B are associated with Coffin–Siris syndrome.

[6][7] Somatic mutations in ARID1B are associated with several cancer subtypes, suggesting that it is a tumor suppressor gene.

[13] This article incorporates text from the United States National Library of Medicine, which is in the public domain.