47611928ENSG00000163399ENSMUSG00000033161P05023Q5TC02Q8VDN2NM_000701NM_001001586NM_001160233NM_001160234NM_144900NP_000692NP_001153705NP_001153706NP_659149Sodium/potassium-transporting ATPase subunit alpha-1 is an enzyme that in humans is encoded by the ATP1A1 gene.

[5] The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases.

These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle.

Alternatively spliced transcript variants encoding different isoforms have been identified.

[5] In melanocytic cells ATP1A1 gene expression may be regulated by MITF.