ATP1A2

47798660ENSG00000018625ENSMUSG00000007097P50993Q6PIE5NM_000702NM_178405NP_000693NP_848492Sodium/potassium-transporting ATPase subunit alpha-2 is a protein which in humans is encoded by the ATP1A2 gene.

[5][6] The protein encoded by this gene belongs to the family of P-type cation transport ATPases and to the subfamily of Na+/K+-ATPases.

These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle.

[6] Mutations in ATP1A2 have been found to cause hemiplegic migraine and epilepsy in an autosomal dominant fashion, sometimes co-occurring in families.

[7] Additionally, it has been associated with an unusual form of migraine called alternating hemiplegia of childhood.