Acquedolci (Sicilian: Acquaduci) is an Italian town and comune in the Metropolitan City of Messina in Sicily.

The inhabited centre was founded in 1922, following a landslide which damaged the town of San Fratello, forcing a large part of the population to relocate there.

The history of Acquedolci has ancient origins that date back to Roman times.

The name itself seems to derive from the fact that the ancient Romans, during the First Punic War, between 264 and 241 BC, identified an underwater spring off the coast that allowed them to supply water directly into the sea.

During the Roman era, Acquedolci, crossed by the Consular Valeria, was a resting place where it was possible to change mules and exchange mail.