Adiposogenital dystrophy is a condition that may be caused by tertiary hypogonadism originating from decreased levels in GnRH.

Low levels of GnRH has been associated with defects of the feeding centers of the hypothalamus[citation needed], leading to an increased consumption of food and thus caloric intake.

It is characterized by:[citation needed] It is usually associated with tumors of the hypothalamus, causing increased appetite and depressed secretion of gonadotropin.

[citation needed] Laboratory analysis of the urine from children with Froehlich syndrome typically reveals low levels of pituitary hormones, and that finding may suggest the presence of a lesion on the pituitary.

Additional tests are needed before a definite diagnosis of Froehlich syndrome may be made.