Alanine dehydrogenase (EC 1.4.1.1) is an enzyme that catalyzes the chemical reaction The 2 substrates of this enzyme are L-alanine, water, and nicotinamide adenine dinucleotide+ because water is 55M and does not change, whereas its 4 products are pyruvate, ammonia, NADH, and hydrogen ion.
This enzyme participates in taurine and hypotaurine metabolism and reductive carboxylate cycle (CO2 fixation).
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor.
The systematic name of this enzyme class is L-alanine:NAD+ oxidoreductase (deaminating).
T Alanine dehydrogenase contains both a N-terminus[1] and C-terminus domains.