Albomycin

Albomycins are a group of naturally occurring antibiotics belonging to the class of sideromycins, which are "compounds composed of iron carriers called siderophores linked to antibiotic moieties".

[1][2] In 2000 a group of scientists from SmithKline Beecham Pharmaceuticals, UK reported that the antibiotic part of albomycin in vitro can inhibit seryl-tRNA synthetase from both eukaryotic and prokaryotic representatives.

[3] Albomycins are naturally occurring sideromycins produced by some streptomycetes.

It contains three molecules of δ-N-hydroxy-δ-N-acetyl ornithine linked to a serine, all by peptide linkage.

The trihydroxamate part serves the siderophore function as it can trap Fe+3 and is essential for active transport of the antibiotic.

Albomycin δ2 bound to iron