This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of the donor with oxygen as the acceptor.

[1] SCAO is capable of oxidizing alcohols with up to 8 carbons, but their primary substrates are methanol and ethanol.

Known inhibitors of this enzyme include H2O2, Cu2+, phenanthroline, acetamide, potassium cyanide, or cyclopropanone.

Nine SCAO isoforms have been found in Ogataea methanolica, which has been shown to be a result of different combinations of two different subunits in the octamers, each coded by a different gene.

[1] As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes 1AHU, 1AHV, 1AHZ, 1VAO, 1W1J, 1W1K, 1W1L, 1W1M, and 2VAO.