Alexandria Prophthasia (Greek: Αλεξάνδρεια η Προφθασία) also known as Alexandria in Drangiana was one of the seventy-plus cities founded or renamed by Alexander the Great.

[1] The town was founded during an intermediate stop between Herat, in what is now Afghanistan, the location of another of Alexander's fortresses, and Kandahar.

[2][3] It is mentioned by Strabo,[4] Pliny the Elder,[5] Ammianus Marcellinus,[6] Isidore of Charax,[7] Stephanus of Byzantium[8] and Pseudo-Plutarch.

[9] Alexander the Great, arrived in Drangiana in November 330 BC on his way to Kandahar, and found a well-organized province of the Achaemenid empire.

[10][11] He appointed a new satrap, Arsames, and renamed the capital city as Prophthasia, ("Anticipation"), because Alexander had here discovered a conspiracy against his life, organized by his companion Philotas.