She was Duchess consort of Bavaria, by her marriage to Rudolf I, Duke of Upper Bavaria.Mechtild was the youngest of eight children, however only Mechtild and three other siblings lived to adulthood: Gerlach I of Nassau-Wiesbaden, Walram III of Nassau-Wiesbaden and Adelheid, Abbess of Klarenthal Abbey.
Rudolf succeeded his father in 1294 and supported his father-in-law king Adolf of Nassau-Weilburg against his uncle, the Habsburg Albert of Austria.
After Adolf’s death Rudolf joined Albert’s party but the strong dynastic policy of the new king caused a new conflict.
A civil war against Louis due to new disputes on the partition of Bavaria was ended in 1313, when peace was made at Munich.
Louis IV, Holy Roman Emperor had taken the Palatinate by force of arms.