[2][3] Her maternal grandparents were James II of Aragon and Blanche of Anjou.

It was important for Anna to marry since her elder siblings, Frederick and Elizabeth, had died without children.

Anna was originally engaged to the future Casimir III the Great, son of Władysław I the Elbow-high and Jadwiga of Greater Poland, but the plans collapsed after Frederick was defeated at the Battle of Mühldorf.

The marriage was short; Henry died in 1333 and the couple had no issue.

By the time of his death, Anna's father had been deposed from the throne of Germany and had been succeeded by his rival, Louis IV, Holy Roman Emperor.