Amalia was born in Braunfels as a fourth daughter of Imperial Count Johann Albrecht I of Solms-Braunfels (1563-1623) and his wife, Countess Agnes of Sayn-Wittgenstein (1568-1617).

She was a member of the House of Solms, a ruling family with Imperial immediacy, and spent her childhood at Braunfels Castle.

The end of their journey was The Hague, where stadtholder Maurice, Prince of Orange, uncle of the elector gave them asylum in 1621.

They often appeared at his court, where Maurice's younger half-brother Frederick Henry, Prince of Orange became infatuated with Amalia in 1622.

When Frederick Henry became stadtholder after the death of his half-brother Prince Maurice, his influence grew substantially, as did Amalia's.

[3] Amalia was supported against Mary by her son-in-law, the Elector of Brandenburg, and she was on good terms with the Grand Pensionary Johan de Witt, a relationship which did not change with the Act of Seclusion of 1654, barring the prince from all ancestral offices.

Amalia retired and witnessed him becoming stadholder of Holland, Zeeland, Utrecht, Gelderland and Overijssel and captain-general of the Union.

Her grandson, William III, King of England, provided refuge and support to thousands of French Huguenots after the revocation of the Edict of Nantes in 1685.