Obtaining a pharmaceutical grade material is difficult due to high amounts of by-products, synthetic intermediates and decomposition products.
administration, but the problem with oral administration is that one experimental study shows there is only a 35–50% absorption while another study shows 40% in the intestines; these results would tend to lead the reader to think that ambazone would not be the best choice for treatment, because with such a low absorbance, there is going to have to be a greater concentration ingested to gain a positive effect from the drug.
It was stated above that ambazone possess no CNS side-effects due to the fact, that it will not cross the blood brain barrier.
When administered orally the results showed prolongation of life expectancy and curing of L1210 and P388 leukemia in lab rats.
The results show two different paths and until further testing has been performed it cannot be determined if the good outweighs the bad when it comes to using ambazone for treatment.