[4][5] Boafo's portraits focus on posture, clothing, and the stroke[clarification needed] of skin which he accentuates with the finger painting technique.

[6][7] In 2019, Boafo participated in a residency at the new Rubell Museum in Miami, Florida, and in 2020 collaborated with Dior for their Spring/Summer 2021 Men Collection.

[8][9][10] His work Suborbital Tryptych, consisting of three portraits of himself, his mother, and a friend's mother, was printed on the top of the crew capsule of a New Shepard rocket that performed an unmanned suborbital launch on August 26, 2021, reaching outer space with an apogee of 106 km.

[11] On 26 May 2022, his debut U.S. exhibit, Soul of Black Folks, opened at Contemporary Art Museum Houston.

[13][14][15] Group exhibitions: Boafo is represented by Mariane Ibrahim Gallery in Chicago and Roberts Projects in Los Angeles.