He was one of the most important followers of Leonardo da Vinci, and brother of Cristoforo Solari, who gave him his first training whilst employed extensively on work at the Milan cathedral, and at the Certosa di Pavia.
[3] Solari's earliest dated work is a Holy Family and St. Jerome with a fine landscape background, executed at Murano in 1495 and now in the Brera Gallery.
In 1507 Andrea Solari went to France with letters of introduction to the Cardinal of Amboise, and was employed for two years on frescoes in the chapel of his castle of Gaillon in Normandy.
[4] According to Giovanni Morelli's suggestion,[5] the artist may have visited Flanders before returning to his native country, and this may account for the Flemish character of his later work.
Andrea's last work was an altarpiece representing The Assumption of the Virgin for the Certosa di Pavia, left unfinished at his death and completed by Bernardino Campi about 1576.